Fig. 2

Cardiovascular risk factors attributed to rheumatoid arthritis. a The table shows patient characteristics of the RA cohort. Forest plots show the difference between IGF1^low (n = 96) and IGF1^hi (n = 88) groups in RA-specific parameters (b) and in anti-rheumatic treatment (c). Lines indicate odds ratio (OR) with 95% confidence interval (CI). The p-values are obtained by chi-square statistics. d The comparison of clinical and serological parameters between IGF1^low (filled boxes) and IGF1^hi (open boxes) groups. Box plots show median, interquartile range. P-values are calculated with the Mann-Whitney U test. RA, rheumatoid arthritis; ESR, erythrocyte sedimentation rate; DD, disease duration, DAS28, disease activity score with assessment of 28 joints; RF, rheumatoid factor; ACPA, antibodies to cyclic citrullinated peptides; MTX, methotrexate; DMARDs, disease modifying anti-rheumatic drugs; TNFi, tumor necrosis factor inhibitors