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Fig. 4 | BMC Medicine

Fig. 4

From: RTS,S/AS01E immunization increases antibody responses to vaccine-unrelated Plasmodium falciparum antigens associated with protection against clinical malaria in African children: a case-control study

Fig. 4

Association between IgG responses to non-RTS,S antigens and malaria protection. a Antigen groups i and ii. b Antigen group iii. Levels of IgG and change from pre- (M0) to post-vaccination (M3). Some representative examples of the distinct patterns observed in each group are shown. Boxplots illustrate the medians and the 25th and 75th quartiles, whiskers display 1.5 times interquartile ranges, and diamonds show the geometric mean. Groups were compared through t tests and p values corrected for multiple comparisons using the Holm approach are shown. M malaria, NM no malaria, log10 MFI log10 of the median fluorescence intensity (MFI) levels measured by quantitative suspension array technology, M3-M0 change between M0 and M3 antibody levels expressed as log10 MFI

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