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Fig. 5 | BMC Medicine

Fig. 5

From: RTS,S/AS01E immunization increases antibody responses to vaccine-unrelated Plasmodium falciparum antigens associated with protection against clinical malaria in African children: a case-control study

Fig. 5

Association between IgG levels to non-RTS,S antigens and malaria protection stratified by age and site. a Antigen groups i and ii. b Antigen group iii. Change from pre- (M0) to post-vaccination (M3) antibody levels. Some representative examples are shown. Boxplots illustrate the medians and the 25th and 75th quartiles, whiskers display 1.5 times interquartile ranges, and diamonds show the geometric mean. Groups were compared through t tests and p values corrected for multiple comparisons using the Holm approach are shown. M malaria, NM no malaria, M3-M0 change between M0 and M3 antibody levels expressed as log10 of the median fluorescence intensity (MFI) measured by quantitative suspension array technology

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