Skip to main content

Table 1 Selected model parameters for post-calibration sensitivity analysis

From: Informing decision-making for universal access to quality tuberculosis diagnosis in India: an economic-epidemiological model

ParametersBase valueLow boundHigh boundReference
Xpert diagnostic accuracy
 Sensitivity—smear positive0.980.931.00[3]
 Sensitivity—smear negative0.670.600.85
 Sensitivity—RIF resistance0.950.900.97
 Specificity—diagnosis of TB disease0.990.981.00
 Specificity—RIF resistance0.980.971.00
Treatment and linkage to care
 Probability of empiric treatment at initial encounter0.250.000.50Assumption
 Probability of loss to follow-up after initial encounter0.130.050.25[10]
 Monthly rate of returning for follow-up encounter0.460.300.70[20]
 Probability of treatment failure for drug-resistant TB0.170.100.25WHO 2016
 Probability of referring from private provider to public sector0.670.540.80[21]
Type of costs
 Cost of initial encounter$12.11$9.08$15.14Recalculated based on [19, 22, 23]
 Cost of follow-up encounter$9.53$7.15$11.91
 Cost of encounter to assess failing treatment$7.39$5.54$9.24
 Other visits (informal/private)$2.32$2.06$2.60
 DS-TB treatment, per 6-month course$345.65$259.24$432.06
 DR-TB treatment, per course$3399.22$2549.41$4249.02
  1. One-way sensitivity analysis was performed by varying each parameter in this table individually between its low and high bounds. For a list of all parameters and references, see Section S2.6 of Additional file 1