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Table 1 AGREE II scores

From: A systematic review of clinical guidelines on the management of acute, community-acquired CNS infections

Guidelines

Scope and purpose (%)

Stakeholder involvement (%)

Rigour of development (%)

Clarity of presentation (%)

Applicability (%)

Editorial independence (%)

Overall quality

Viral aetiology

 IEC

91.7

63.9

40.6

91.7

52.1

50.0

5

 EFNS

83.3

52.8

55.2

91.7

47.9

25.0

5

 DNS

38.7

27.7

22.1

41.8

16.6

0.0

3

 DGN: VM

69.4

44.4

50.0

75.0

20.8

66.7

5

 IDSA

72.2

50.0

58.3

86.1

18.8

83.3

6

 PHE: VE

88.9

75.0

44.8

86.1

31.3

50.0

6

 BIA: ABN

100

83.3

94.8

94.4

47.9

66.7

6

 BIA: ABN/BPAIIG

100

83.3

74.0

91.7

54.2

0.0

6

 AEPED

61.1

33.3

24.0

55.6

20.8

8.3

3

 SPILF

78

41.5

45.5

75.0

4.0

8.3

4

 Median

80.7

51.4

47.8

86.1

26.1

37.5

5.0

 Range

(39–100)

(22–83)

(22–95)

(42–94)

(17–54)

(0–83)

(3–6)

Viral and bacterial aetiology

 NNF

75.0

52.8

37.5

88.9

6.3

29.2

4

 PHE: ME

97.2

69.4

28.1

94.4

43.8

83.3

5

 Median

86.1

61.1

32.8

91.7

25.1

56.3

4.5

 Range

(75–97)

(52–69)

(28–38)

(89–94)

(6–44)

(29–83)

(4–5)

Bacterial aetiology

 EFNS

94.4

52.8

47.9

97.2

43.8

0.0

5

 ESCMID

100

83.3

88.5

88.9

47.9

66.7

7

 DSI

75.0

36.1

20.8

86.1

45.8

0.0

4

 SPILF

83.3

38.9

44.8

88.9

25.0

0.0

4

 DGN: BM

69.4

44.4

50.0

75.0

20.8

66.7

5

 HPSC

100

66.7

45.8

94.4

39.6

0.0

5

 NVN

97.2

94.4

87.6

97.2

66.7

29.2

7

 MHSSE

100

94.4

90.6

86.1

43.8

50.0

7

 NICE

100

86.1

95.8

88.9

79.2

70.8

7

 UKJSS

100

88.9

77.1

94.4

47.9

50.0

7

 SIGN

91.7

91.7

79.2

86.1

37.5

45.8

7

 IDSA

75.0

50.0

59.4

86.1

10.4

54.2

5

 AEPED

61.1

33.3

19.8

83.3

20.8

0.0

3

 MSF

88.9

47.2

9.4

91.7

50.0

0.0

4

 Median

93.1

59.8

54.7

88.9

43.8

37.5

5

 Range

(61–100)

(33–94)

(9–96)

(75–97)

(10–79)

(0–71)

(3–7)

  1. Abbreviations: IEC International Encephalitis Consortium, EFNS European Federation of Neurological Societies, DNS Dansk Neurologisk Selskab, DGN: VM Deutsche Gesellschaft für Neurologie: Virale Meningoeczephalitis, PHE: VE Public Health England: Viral Encephalitis, BIA: ABN British Infection Association: Association of British Neurologists, BPAIIG The British Paediatric Allergy Immunology and Infections Group, AEPED Asociación Española de Pediatría, SPILF Société de Pathologie Infectieuse de Langue Française, PHE: ME Public Health England: Meningoencephalitis, NNF Norsk Nevrologisk Forening, ESCMID European Society of Clinical Microbiology and Infectious Diseases, DSI Dansk Selskab for Infektionsmedicin, DGN: BM Deutsche Gesellschaft für Neurologie: Bakterielle Meningoenzephalitis, HPSC Health Protection Surveillance Centre, NVN Nederlandse Vereniging voor Neurologie, MHSSE Ministry of Health, Social Services and quality, NICE The National Institute for Health and Care Excellence, UKJSS UK Joint Specialist Societies, SIGN Scottish Intercollegiate Guidelines Network, IDSA Infectious Diseases Society of America, MSF Médecins Sans Frontières