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Table 1 Basic characteristics of cases and controls

From: Antibiotic use and the risk of rheumatoid arthritis: a population-based case-control study

Variable Controls (n = 90,013) RA cases (n = 22,677)
N % N %
Year of RA diagnosis
 1995–1999 8086 9 2033 9
 2000–2004 15,253 16.9 3849 17
 2005–2009 24,713 27.5 6232 27.5
 2010–2014 31,699 35.2 7980 35.2
 2015–2017 10,262 11.4 2583 11.4
Age at index (years)
 < 40 19,064 21.2 4857 21.4
 40–59 20,416 22.7 5095 22.5
 60–69 22,257 24.7 5588 24.6
 70–79 19,238 21.4 4843 21.4
 80–89 8366 9.3 2093 9.2
 ≥ 90 672 0.7 201 0.9
Mean age (SD) 61.4 (14.1) 61.4 (14.3)
Gender, female 60,620 67.3 15,276 67.4
Median follow-up before RA diagnosis (IQR) 10 (7–14) 10 (7–14)
Body mass index
 Underweight 22,337 24.8 5102 22.5
 Normal 2402 2.7 694 3.1
 Overweight 28,948 32.2 7456 32.9
 Obese 24,610 27.3 7308 32.2
 Missing 11,716 13 2117 9.3
Smoking status
 Never/ex-smokers 74,043 82.3 17,840 78.7
 Current 15,970 17.7 4837 21.3
Alcohol
 Never/ex-drinker 29,159 32.4 7341 32.4
 1–10 units/weeks 46,692 51.9 11,976 52.8
 > 10 units/week 14,162 15.7 3360 14.8
Charlson comorbidity index
 0 56,683 63 12,813 56.5
 1–2 24,356 27.1 7219 31.8
 3–5 7937 8.8 2355 10.4
 > 5 1037 1.2 290 1.3