Univariable | Multivariable | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Variable | Category | Coeff | SE | SHR | 95% CI | p | Coeff | SE | SHR | 95% CI | p |
Tumour size | 0.1–4.0 cm | Reference | Reference | ||||||||
4.1–10.0 cm | 1.64 | 0.34 | 5.15 | 2.60–10.2 | < 0.001 | 1.00 | 0.38 | 2.73 | 1.31–5.68 | 0.007 | |
> 10 cm | 2.52 | 0.40 | 12.38 | 5.63–27.2 | < 0.001 | 1.09 | 0.49 | 2.97 | 1.14–7.74 | 0.026 | |
T stage | pT1 | Reference | Reference | ||||||||
pT2 | 1.47 | 0.41 | 4.36 | 1.94–9.8 | < 0.001 | 0.69 | 0.44 | 1.99 | 0.84–4.69 | 0.12 | |
pT3 | 2.09 | 0.30 | 7.99 | 4.48–14.3 | < 0.001 | 0.91 | 0.36 | 2.48 | 1.21–5.05 | 0.013 | |
pT4 | 4.22 | 0.28 | 68.3 | 39.4–118.4 | < 0.001 | 1.15 | 0.63 | 3.15 | 0.92–10.8 | 0.068 | |
N stage | pNx/pN0 | Reference | Reference | ||||||||
pN1 | 2.55 | 0.36 | 12.8 | 6.37–25.9 | < 0.001 | 1.49 | 0.46 | 4.42 | 1.78–11.0 | 0.001 | |
Nuclear grade | G1 or G2 | Reference | Reference | ||||||||
G3 or G4 | 1.55 | 0.26 | 4.73 | 2.85–7.87 | < 0.001 | 0.93 | 0.30 | 2.53 | 1.42–4.53 | 0.002 | |
Venous tumour thrombus | Absent | Reference | Reference | ||||||||
Renal vein | 2.15 | 0.48 | 8.56 | 3.32–22.1 | < 0.001 | 1.07 | 0.49 | 2.93 | 1.12–7.67 | 0.029 | |
IVC | 2.44 | 0.35 | 11.5 | 5.77–23.0 | < 0.001 | 0.95 | 0.45 | 2.57 | 1.08–6.16 | 0.034 | |
Papillary type | Type 1 | Reference | |||||||||
Type 2 | 1.07 | 0.31 | 2.91 | 1.58–5.34 | < 0.001 | ||||||
Fat invasion | Present | 0.93 | 0.28 | 2.53 | 1.47–4.33 | < 0.001 | |||||
Tumour necrosis | Present | 1.01 | 0.27 | 2.74 | 1.61–4.67 | < 0.001 | |||||
Sarcomatoid features | Present | 1.33 | 0.57 | 3.77 | 1.24–11.5 | 0.019 | |||||
Surgical margin | Positive | 0.45 | 0.46 | 1.56 | 0.63–3.86 | 0.34 |