Fig. 1
From: Synthetic high-density lipoprotein nanoparticles for the treatment of Niemann–Pick diseases
Synthesis and characterization of sHDL nanoparticles. a A lyophilized mixture of 5A peptide and sphingomyelin (SM) was hydrated in PBS and thermocycled to assemble sHDL particles. b, c Particle size distribution was analyzed by b dynamic light scattering for 1 mg/mL of 5A-SM, 5A-DMPC, or 5A-POPC sHDL or c transmission electron microscopy of 5A-SM, 5A-DMPC, and 5A-POPC. Scale bar = 100 nm