| Small size for gestational age |  | Large size for gestational age |  | ||
---|---|---|---|---|---|---|
Customized onlya | Customized and populationb | p value | Customized onlya | Customized and populationb | p value | |
n = 150 | n = 455 |  | n = 129 | n = 476 |  | |
Maternal characteristics | ||||||
 Age, median (95% range), years | 30.5 (20.4 to 39.0) | 30.5 (19.6 to 40.3) | 0.215 | 27.7 (19.9 to 36.0) | 31.2 (20.7 to 40.0) | < 0.001 |
 Height, mean (SD) (cm) | 169.0 (7.8) | 165.3 (7.0) | < 0.001 | 165.7 (6.4) | 170.3 (7.2) | < 0.001 |
 Weight, mean (SD) (kg) | 85.4 (18.1) | 67.3 (12.8) | < 0.001 | 60.8 (7.6) | 72.9 (12.8) | < 0.001 |
 Body mass index, mean (SD) (kg/m2) | 30.0 (6.5) | 24.6 (4.6) | < 0.001 | 22.2 (2.5) | 25.2 (4.6) | < 0.001 |
 Obesity, no. (%) | 67 (44.7) | 56 (12.3) | < 0.001 | 2 (1.6) | 58 (12.2) | < 0.001 |
 Education, no. higher (%) | 51 (34.0) | 166 (36.5) | 0.582 | 57 (44.2) | 249 (52.3) | 0.102 |
 Race/ethnicity, no. (%) Dutch or European | 101 (67.3) | 253 (55.6) | 0.011 | 56 (43.4) | 327 (68.7) | < 0.001 |
 Parity, no. nulliparous (%) | 50 (33.3) | 298 (65.5) | < 0.001 | 108 (83.7) | 222 (46.6) | < 0.001 |
 Smoking, no. (%) |  |  | 0.055 |  |  | 0.711 |
  None | 109 (75.2) | 282 (64.5) |  | 100 (80.0) | 366 (79.2) |  |
  Early pregnancy only | 9 (6.2) | 33 (7.6) |  | 14 (11.2) | 45 (9.7) |  |
  Continued | 27 (18.6) | 122 (27.9) |  | 11 (8.8) | 51 (11.0) |  |
Birth characteristics | ||||||
 Males, no. (%) | 67 (44.7) | 185 (40.7) | 0.388 | 72 (55.8) | 281 (59.0) | 0.511 |
 Gestational age, median (95% range), weeks | 40.1 (32.6 to 42.4) | 39.6 (31.9 to 42.3) | 0.007 | 40.0 (36.4 to 42.4) | 39.9 (36.1 to 42.0) | 0.058 |
 Birth weight, mean (SD) grams | 2981 (412) | 2503 (445) | < 0.001 | 3922 (319) | 4245 (386) | < 0.001 |
 Preterm birth, no. (%) | 12 (8.0) | 62 (13.6) | 0.068 | 3 (2.3) | 18 (3.8) | 0.423 |
 Cesarean delivery, no. (%) | 19 (13.4) | 88 (20.8) | 0.051 | 20 (16.7) | 74 (17.2) | 0.897 |
 Assisted delivery, no. (%) | 9 (6.3) | 66 (15.6) | 0.005 | 27 (22.5) | 48 (11.1) | 0.001 |
 APGAR score below 7 at 5 min, no. (%) | 5 (3.4) | 11 (2.5) | 0.549 | 0 (0) | 5 (1.1) | 0.237 |