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Table 3 Maternal and birth characteristics of SGA or LGA newborns by customized charts only compared to newborns classified as SGA or LGA by both classifications

From: Customized versus population birth weight charts for identification of newborns at risk of long-term adverse cardio-metabolic and respiratory outcomes: a population-based prospective cohort study

 

Small size for gestational age

 

Large size for gestational age

 

Customized onlya

Customized and populationb

p value

Customized onlya

Customized and populationb

p value

n = 150

n = 455

 

n = 129

n = 476

 

Maternal characteristics

 Age, median (95% range), years

30.5 (20.4 to 39.0)

30.5 (19.6 to 40.3)

0.215

27.7 (19.9 to 36.0)

31.2 (20.7 to 40.0)

< 0.001

 Height, mean (SD) (cm)

169.0 (7.8)

165.3 (7.0)

< 0.001

165.7 (6.4)

170.3 (7.2)

< 0.001

 Weight, mean (SD) (kg)

85.4 (18.1)

67.3 (12.8)

< 0.001

60.8 (7.6)

72.9 (12.8)

< 0.001

 Body mass index, mean (SD) (kg/m2)

30.0 (6.5)

24.6 (4.6)

< 0.001

22.2 (2.5)

25.2 (4.6)

< 0.001

 Obesity, no. (%)

67 (44.7)

56 (12.3)

< 0.001

2 (1.6)

58 (12.2)

< 0.001

 Education, no. higher (%)

51 (34.0)

166 (36.5)

0.582

57 (44.2)

249 (52.3)

0.102

 Race/ethnicity, no. (%) Dutch or European

101 (67.3)

253 (55.6)

0.011

56 (43.4)

327 (68.7)

< 0.001

 Parity, no. nulliparous (%)

50 (33.3)

298 (65.5)

< 0.001

108 (83.7)

222 (46.6)

< 0.001

 Smoking, no. (%)

  

0.055

  

0.711

  None

109 (75.2)

282 (64.5)

 

100 (80.0)

366 (79.2)

 

  Early pregnancy only

9 (6.2)

33 (7.6)

 

14 (11.2)

45 (9.7)

 

  Continued

27 (18.6)

122 (27.9)

 

11 (8.8)

51 (11.0)

 

Birth characteristics

 Males, no. (%)

67 (44.7)

185 (40.7)

0.388

72 (55.8)

281 (59.0)

0.511

 Gestational age, median (95% range), weeks

40.1 (32.6 to 42.4)

39.6 (31.9 to 42.3)

0.007

40.0 (36.4 to 42.4)

39.9 (36.1 to 42.0)

0.058

 Birth weight, mean (SD) grams

2981 (412)

2503 (445)

< 0.001

3922 (319)

4245 (386)

< 0.001

 Preterm birth, no. (%)

12 (8.0)

62 (13.6)

0.068

3 (2.3)

18 (3.8)

0.423

 Cesarean delivery, no. (%)

19 (13.4)

88 (20.8)

0.051

20 (16.7)

74 (17.2)

0.897

 Assisted delivery, no. (%)

9 (6.3)

66 (15.6)

0.005

27 (22.5)

48 (11.1)

0.001

 APGAR score below 7 at 5 min, no. (%)

5 (3.4)

11 (2.5)

0.549

0 (0)

5 (1.1)

0.237

  1. Values are median (95% range), mean (SD), and absolute numbers (%), and p values for comparison between population only and customized and population classification. Continuous variables were tested using ANOVA; categorical variables were tested using Chi2 tests
  2. SD standard deviation
  3. aAs defined by the population birth weight classification, but appropriately sized according to customized birth weight classification
  4. bAs defined by the both customized and population birth weight classification