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Table 4 Costs of outcomes when making a decision based on a risk threshold

From: Three myths about risk thresholds for prediction models

  Diseased Not diseased
Intervene (predicted risk ≥t) CTP = 15
The cost of detected/treated disease, e.g., risk of death or severe morbidity despite detection, plus the cost of intervening
CFP = 5
The cost of an unneeded intervention, e.g., invasiveness of testing, complication risks of treatment
Do not intervene
(predicted risk <t)
CFN = 95
The cost of an undetected disease, i.e., the risk of death or severe morbidity
CTN = 0
The cost of applying the risk model