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Table 1 Trial participants and community patients with each index condition

From: Representation of people with comorbidity and multimorbidity in clinical trials of novel drug therapies: an individual-level participant data analysis

Index condition

Trials

Trial participants

Community-based sample

Cardiometabolic

 Type 2 diabetes mellitus

21

23,750

82,473

 Atrial fibrillation

1

18,033

43,330

 Hypertension

8

5151

310,691

 Thromboembolism

4

9362

9162

Respiratory

 Asthma

4

1623

191,160

 COPD

7

5256

57,378

 Pulmonary fibrosis

2

1063

1465

 Pulmonary hypertension

1

406

759

Inflammatory

 Axial spondyloarthritis

2

458

1982

 Inflammatory bowel disease

12

9241

12,514

 Psoriasis

7

7568

52,810

 Psoriatic arthritis

3

1331

3523

 Rheumatoid arthritis

11

7662

13,809

 Systemic lupus erythematosus

2

1693

1033

Musculoskeletal

 Osteoarthritis

1

1320

124,521

 Osteoporosis

7

14,497

38,212

Neurological

 Dementia

7

6253

13,871

 Migraine

5

3069

19,562

 Parkinson’s disease

3

1368

4727

 Restless legs syndrome

2

676

11,480

Urological

 Benign prostatic hyperplasia

5

2210

19,906

 Erectile dysfunction

1

606

65,736