Composite and subtest scores | Placebo (n = 33) | Folic acid (n = 37) | Difference | p value (unadjusted)a | p value (adjusted)b |
---|---|---|---|---|---|
Verbal IQ | 103.4 (99.4, 107.4) | 107.7 (103.7, 111.8) | 4.3 (− 1.2, 9.9) | 0.126 | 0.120 |
Information | 10.9 (9.9, 11.8) | 11.1 (10.3, 12.0) | 0.3 (− 1.0, 1.5) | 0.648 | 0.630 |
Vocabulary | 9.6 (8.9, 10.4) | 10.3 (9.5, 11.1) | 0.7 (− 0.4, 1.8) | 0.221 | 0.262 |
Word reasoning | 11.9 (11.0, 12.8) | 13.3 (12.4, 14.2) | 1.4 (0.2, 2.6) | 0.023 | 0.027 |
Performance IQ | 100.6 (96.5, 104.6) | 104.1 (99.1, 109.1) | 3.5 (− 2.9, 9.8) | 0.274 | 0.429 |
Processing speed | 103.9 (98.1, 109.7) | 102.5 (97.4, 107.7) | 1.4 (− 6.2, 8.9) | 0.718 | 0.712 |
General language | 105.8 (101.1, 110.5) | 108.9 (104.5, 113.2) | 3.1 (− 3.2, 9.4) | 0.334 | 0.514 |
Full scale IQ | 103.5 (99.3, 107.6) | 106.4 (101.7, 111.1) | 3.0 (− 3.3, 9.2) | 0.348 | 0.441 |