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Table 1 The characteristics of the study population (n = 1442)

From: In utero exposure to mercury and childhood overweight or obesity: counteracting effect of maternal folate status

 

Maternal RBC mercury level (μg/L) in quartiles

Q1

0·39–1·04

Q2

1·02–2·10

Q3

2·12–3·68

Q4

3·70–27·8

P trend

Maternal characteristics

n

360

361

359

362

 

Age, years

26·8 ± 6·5

28·0 ± 6·0

29·1 ± 6·7

30·3 ± 6·3

< 0·001

Race

    

< 0·001

 Black

192 (53·3)

225 (62·3)

265 (73·8)

285 (78·7)

 

 Non-black

168 (46·7)

136 (37·7)

94 (26·2)

77 (21·3)

 

Education

    

0·367

 High school and less

234 (65·0)

243 (67·3)

233 (64·9)

226 (62·4)

 

 Beyond high school

126 (35·0)

118 (32·7)

126 (35·1)

136 (37·6)

 

Smoking

    

< 0·001

 Not smoker

279 (77·5)

284 (78·7)

305 (85·0)

324 (89·5)

 

 Smoker

81 (22·5)

77 (21·3)

54 (15·0)

38 (10·5)

 

Parity

    

0·001

 Nulliparous

177 (49·2)

150 (41·6)

139 (38·7)

136 (37·6)

 

 Multiparous

183 (50·8)

211 (58·4)

220 (61·3)

226 (62·4)

 

 Pre-pregnancy BMI, kg/m2

26·4 ± 6·8

27·2 ± 7·6

27·2 ± 6·7

26·5 ± 5·7

0·769

 Overweight or obesity

176 (48·9)

185 (51·2)

203 (56·6)

197 (54·4)

0·063

 Diabetes

44 (12·2)

45 (12·5)

45 (12·5)

50 (13·8)

0·537

 Hypertensive disorder

45 (12·5)

50 (13·9)

61 (17·0)

60 (16·6)

0·068

Fish intake (serving/week)

    

< 0·001

 0

163 (45·3)

80 (22·2)

55 (15·3)

35 (9·7)

 

 1–2

183 (50·8)

253 (70·1)

246 (68·5)

239 (66·0)

 

 ≥ 3

14 (3·9)

28 (7·7)

58 (16·2)

88 (24·3)

 

 Plasma folate (nmol/L)*

34·6 (32·5–36·8)

30·1 (28·3–32·1)

29·4 (27·5–31·3)

30·7 (28·8–32·7)

< 0·001

Child’s characteristics

Age, years

7·6 ± 2·9

8·0 ± 3·2

8·6 ± 3·3

8·4 ± 3·0

0·001

Gender

    

0·002

 Boy

196 (54·4)

190 (52·6)

180 (50·1)

156 (43·1)

 

 Girl

164 (45·6)

171 (47·4)

179 (49·9)

206 (56·9)

 

Birthweight, g

2982 ± 773

2955 ± 776

2972 ± 790

3015 ± 818

0·775

Gestational age, weeks

38·0 ± 3·2

37·9 ± 3·3

37·8 ± 3·2

38·1 ± 3·1

0·998

Preterm birth

88 (24·4)

90 (24·9)

85 (23·7)

85 (23·5)

0·681

Fetal growth

    

0·176

 AGA

290 (80·6)

286 (79·2)

279 (77·7)

281 (77·6)

 

 SGA

38 (10·5)

37 (10·3)

39 (10·9)

37 (10·2)

 

 LGA

32 (8·9)

38 (10·5)

41 (11·4)

44 (12·2)

 

Breastfeeding

    

0·013

 Formula only

90 (25·0)

105 (29·1)

88 (24·5)

65 (17·9)

 

 Breastfeed exclusively

28 (7·8)

31 (8·6)

21 (5·9)

39 (10·8)

 

 Both

242 (67·2)

225 (62·3)

250 (69·6)

258 (71·3)

 

Overweight or obesity

138 (38·3)

154 (42·7)

146 (40·7)

174 (48·1)

0·019

Number of BMI measures

3·8 ± 2·3

4·0 ± 2·5

4·1 ± 2·6

4·0 ± 2·4

< 0·001

  1. *Geometric mean (95% CI); Q quartile, RBC red blood cell, AGA appropriate for gestational age, SGA small for gestational age, LGA large for gestational age