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Table 2 Association of maternal mercury levels with child risk of overweight or obesity

From: In utero exposure to mercury and childhood overweight or obesity: counteracting effect of maternal folate status

Age group

Mercury quartile

  

Crude

Adjusted

n

Case, n(%)

RR

95% CI

p

RR

95% CI

p

Total sample 2–15 years (n = 1442)

 Q1

360

138 (38·3)

1·00

  

1·00

  

 Q2

361

154 (42·7)

1·11

0·93–1·33

0·238

1·09

0·92–1·30

0·313

 Q3

359

146 (40·7)

1·06

0·89–1·27

0·522

1·03

0·86–1·23

0·748

 Q4

362

174 (48·1)

1·25

1·06–1·49

0·009

1·24

1·05–1·47

0·013

 P trend

    

0·047

  

0·098

 Q1–Q3

1080

438 (40·6)

1·00

  

1·00

  

 Q4

362

174 (48·1)

1·19

1·04–1·35

0·010

1·19

1·05–1·35

0·007

2–5 years (n = 1395)

 Q1

346

113 (32·7)

1·00

  

1·00

  

 Q2

347

139 (40·1)

1·23

1·01–1·50

0·044

1·20

0·99–1·45

0·061

 Q3

347

138 (39·8)

1·22

1·00–1·49

0·053

1·15

0·95–1·41

0·160

 Q4

355

159 (44·8)

1·37

1·13–1·66

0·001

1·33

1·10–1·61

0·003

 P trend

    

0·015

  

0·067

 Q1–Q3

1040

390 (37·5)

1·00

  

1·00

  

 Q4

355

159 (44·8)

1·19

1·04–1·37

0·013

1·19

1·03–1·36

0·016

6–9 years (n = 1030)

 Q1

250

100 (40·0)

1·00

  

1·00

  

 Q2

255

118 (46·3)

1·16

0·95–1·41

0·156

1·15

0·94–1·39

0·171

 Q3

258

116 (45·0)

1·12

0·92–1·38

0·259

1·09

0·89–1·34

0·399

 Q4

267

142 (53·2)

1·33

1·10–1·61

0·003

1·30

1·07–1·58

0·007

 P trend

    

0·028

  

0·100

 Q1–Q3

763

334 (43·8)

1·00

  

1·00

  

 Q4

267

142 (53·2)

1·21

1·06–1·40

0·006

1·20

1·04–1·38

0·010

10–15 years (n = 449)

 Q1

91

38 (41·8)

1·00

  

1·00

  

 Q2

106

47 (44·3)

1·06

0·77–1·47

0·716

1·14

0·84–1·56

0·383

 Q3

138

67 (48·6)

1·16

0·86–1·57

0·320

1·22

0·91–1·64

0·184

 Q4

114

62 (54·4)

1·30

0·97–1·75

0·079

1·40

1·04–1·88

0·028

 P trend

    

0·057

  

0·058

 Q1–Q3

335

152 (45·4)

1·00

  

1·00

  

 Q4

114

62 (54·4)

1·20

0·98–1·47

0·083

1·22

0·99–1·50

0·061

  1. Q quartile, RR relative risk, CI conference interval. Mercury quartile range: Q1 0.39–1.04 μg/L; Q2 1.04–2.10 μg/L; Q3 2.12–3.68 μg/L; Q4 3.70–27.8 μg/L.
  2. Adjusted for maternal age, race, smoking, education, parity, pre-pregnancy overweight or obesity, diabetes, hypertensive disorder, preterm birth, fetal growth pattern, and breastfeeding status
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BMC Medicine

ISSN: 1741-7015

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