TY - JOUR AU - Browne, Annie J. AU - Kashef Hamadani, Bahar H. AU - Kumaran, Emmanuelle A. P. AU - Rao, Puja AU - Longbottom, Joshua AU - Harriss, Eli AU - Moore, Catrin E. AU - Dunachie, Susanna AU - Basnyat, Buddha AU - Baker, Stephen AU - Lopez, Alan D. AU - Day, Nicholas P. J. AU - Hay, Simon I. AU - Dolecek, Christiane PY - 2020 DA - 2020/01/03 TI - Drug-resistant enteric fever worldwide, 1990 to 2018: a systematic review and meta-analysis JO - BMC Medicine SP - 1 VL - 18 IS - 1 AB - Antimicrobial resistance (AMR) is an increasing threat to global health. There are > 14 million cases of enteric fever every year and > 135,000 deaths. The disease is primarily controlled by antimicrobial treatment, but this is becoming increasingly difficult due to AMR. Our objectives were to assess the prevalence and geographic distribution of AMR in Salmonella enterica serovars Typhi and Paratyphi A infections globally, to evaluate the extent of the problem, and to facilitate the creation of geospatial maps of AMR prevalence to help targeted public health intervention. SN - 1741-7015 UR - https://doi.org/10.1186/s12916-019-1443-1 DO - 10.1186/s12916-019-1443-1 ID - Browne2020 ER -