Fig. 2

Quantification of plasma lipids in hypercholesterolemic mice, in pre-vaccination (week 0) and after four vaccinations (post-vaccination; week 8) with L-IFPTA⁺ vaccine. Mean and SEM are demonstrated for a total cholesterol, b LDL-C, c VLDL-C, and d triglyceride. Negative control involves hypercholesterolemic mice received free liposomes. Each data point symbolizes an individual mouse; lines represent means for each group. Significance values were calculated by comparison with control values using a two-tailed Student’s t test. LDL-C, low-density lipoprotein cholesterol; VLDL-C, very low-density lipoprotein cholesterol; ns, not significant