Fig. 2

Calibration curves when validating a model for obstructive coronary artery disease before and after updating. a Calibration curve before updating. b Calibration curve after updating by re-estimating the model coefficients. The flexible curve with pointwise confidence intervals (gray area) was based on local regression (loess). At the bottom of the graphs, histograms of the predicted risks are shown for patients with (1) and patients without (0) coronary artery disease. Figure adapted from Edlinger et al. [38], which was published under the Creative Commons Attribution–Noncommercial (CC BY-NC 4.0) license