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Fig. 5 | BMC Medicine

Fig. 5

From: Multi-level transcriptome sequencing identifies COL1A1 as a candidate marker in human heart failure progression

Fig. 5

Gene expression regulatory networks in heart failure. a microRNA-mRNA regulatory network. b lncRNA-mRNA regulatory network. c microRNA-lncRNA-mRNA co-regulatory network. mRNAs, microRNAs, and lncRNAs are denoted by circle, triangle, and pentagon nodes, respectively. Red, orange, and purple nodes are upregulated expression and other color for downregulated expression. The edges represent differently weighted regulation. Edge width is proportional to the Spearman correlation coefficient between the linking nodes. Here, an arrow indicates activation relation while an edge ending with -| indicates repression

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