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Fig. 4 | BMC Medicine

Fig. 4

From: Mass cytometry analysis reveals a distinct immune environment in peritoneal fluid in endometriosis: a characterisation study

Fig. 4

Immune signatures associated with endometriosis and correlated with disease stages. ac Frequencies of macrophages and T cells (a), B cells (b), and NK cells (c) show significant differences at minimal/mild disease stages (see Additional file 1: Figure S9). d Alternative (CD163+/CD206+) and classical (CD40 and CD16) activation markers on macrophages are increased significantly at minimal/mild stages. e Abundances of FceRIa+ B cells are increased at minimal/mild disease stages. f Frequencies of CD206+ and FceRIa+ DCs at stage I are increased. Means ± SEM are shown. The Mann-Whitney U test was used in comparison between control and disease stage samples. *p < 0.05; **p < 0.01; ***p < 0.001. Control, n = 11; stage I, n = 11; stage II, n = 8; stages III and IV, n = 8

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