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Table 1 The predicted 20-year annual average number of clinical events in the Netherlands in the absence and presence of childhood influenza vaccination for children aged 2–16 years at 50% coverage. Events are shown for the entire population and for the targeted age group only

From: Vaccinating children against influenza: overall cost-effective with potential for undesirable outcomes

Outcome

Symptomatic cases

GP visits

Hospitalizations

Deaths

Mean (95% interval)a

Rateb

Mean (95% interval)a

Rateb

Mean (95% interval)a

Rateb

Mean (95% interval)a

Rateb

Within the general population

 CP

317,703 (239,785–391,519)

1781

71,552 (53,140–89,952)

401

7703 (4960–10,391)

43.1

3234 (2057–4475)

18.1

 CP + 2–16 y

260,437 (123,289–354,634)

1460

58,200 (26,929–79,538)

326

6415 (2749–9484)

35.9

2916 (1208–4353)

16.3

 Reduction

57,266 (19,116–116,418)

321

13,352 (5113–25,873)

75

1288 (547–2306)

7.2

318 (− 105 to 844)

1.8

Within children aged 2–16 y

 CP

86,779 (69,895–102,394)

3018

20,546 (15,968–24,684)

714

1480 (934–2018)

51.5

1.6 (.8–2.5)

0.054

 CP + 2–16 y

55,257 (28,278–72,633)

1921

12,918 (6428–17,287)

449

865 (371–1284)

30.1

1.1 (.4–1.9)

0.038

 Reduction

31,522 (21,676–43,348)

1097

7628 (5550–10,111)

265

615 (464–789)

21.4

0.5 (− 0.2 to 1.1)

0.016

  1. aBased on 1000 simulations, 95% interval uses the 2.5% and 97.5% percentiles. bRate per 100,000 population. CP current program, y years