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Table 1 The predicted 20-year annual average number of clinical events in the Netherlands in the absence and presence of childhood influenza vaccination for children aged 2–16 years at 50% coverage. Events are shown for the entire population and for the targeted age group only

From: Vaccinating children against influenza: overall cost-effective with potential for undesirable outcomes

OutcomeSymptomatic casesGP visitsHospitalizationsDeaths
Mean (95% interval)aRatebMean (95% interval)aRatebMean (95% interval)aRatebMean (95% interval)aRateb
Within the general population
 CP317,703 (239,785–391,519)178171,552 (53,140–89,952)4017703 (4960–10,391)43.13234 (2057–4475)18.1
 CP + 2–16 y260,437 (123,289–354,634)146058,200 (26,929–79,538)3266415 (2749–9484)35.92916 (1208–4353)16.3
 Reduction57,266 (19,116–116,418)32113,352 (5113–25,873)751288 (547–2306)7.2318 (− 105 to 844)1.8
Within children aged 2–16 y
 CP86,779 (69,895–102,394)301820,546 (15,968–24,684)7141480 (934–2018)51.51.6 (.8–2.5)0.054
 CP + 2–16 y55,257 (28,278–72,633)192112,918 (6428–17,287)449865 (371–1284)30.11.1 (.4–1.9)0.038
 Reduction31,522 (21,676–43,348)10977628 (5550–10,111)265615 (464–789)21.40.5 (− 0.2 to 1.1)0.016
  1. aBased on 1000 simulations, 95% interval uses the 2.5% and 97.5% percentiles. bRate per 100,000 population. CP current program, y years