Table 4 Minimum inhibitory concentrations of streptomycin for strains with a gidB L79S mutation
From: A landscape of genomic alterations at the root of a near-untreatable tuberculosis epidemic
Isolate | MGIT result (cc = 1 μg/ml) | Mutations |
|---|---|---|
H37RV (control) | 0.5 μg/ml | – |
H37MA (control) | ≤ 0.5 μg/ml | – |
R296 | ≤ 0.5 μg/ml | No gidB |
R3239 | ≤ 0.5 μg/ml | No gidB |
TT372 | ≤ 0.5 μg/ml | No gidB |
TT648 | ≤ 0.5 μg/ml | No gidB |
R9248 | 1.0 μg/ml | gidB L79S |
R18832 | 1.0 μg/ml | gidB L79S |
TT17 | > 2.0 μg/ml | gidB L79S + rrs514c |
TT649 | > 2.0 μg/ml | gidB L79S + rrs514c |
TT321 | > 2.0 μg/ml | gidB L79S + rpsL K43R |
PES16 | 2.0 μg/ml | gidB L79S + rrs1484t |