Association between the cytokine storm, immune cell dynamics, and viral replicative capacity in hyperacute HIV infection

Table 3 Characteristics of participants involved in the determination of complete blood counts at initial detection of viremia

	Pre-infection	Fiebig stages I–II	Fiebig stages III–V	Chronic	P value^a
	Pre-infection	Fiebig stages I–II	Fiebig stages III–V	Chronic	Fiebig stages I–II	Fiebig stages III–V	Chronic
Number of participants	70	60	15	33	N/A	N/A	N/A
Female, N (%)	70 (100%)	60 (100%)	15 (100%)	32 (97%)	1.000	1.000	0.143
Age in years	21.1 (19.8–22.1)	21.2 (19.9–22.5)	22.5 (20.8–23.7)	22.9 (21.4–24.3)	0.508	0.039	< 0.001
Viral load (log10 copies/mL)	N/A	4.20 (3.50–4.92)	6.26 (4.88–7.20)	3.60 (3.04–4.31)	N/A	N/A	N/A
CD4⁺ T cell counts (cells/μL)	891 (751–1047)	763 (538–911)	444 (367–553)	599 (470–756)	< 0.001	< 0.001	< 0.001

Values for age, viral load, and CD4⁺ T cell counts are medians and interquartile ranges
^aStatistical test used: Wilcoxon rank-sum test (Mann-Whitney U test) was used to compare the differences in age and CD4+ T cell counts between pre-infection and post-infection time points. Chi-square test was used to assess the differences in gender distribution