Table 1 Annual numbers of cases of infective endocarditis based on the three different criteria, along with incidence rates and age and sex distribution
Year end | Criteria A (optimising sensitivity/PPV) | Criteria B (optimising specificity/PPV) | Criteria C (used in prior study [6]) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Â | No. of cases | Incidence rate per 1 million population | Percentage male | Median age (IQR) | No. of cases | Incidence rate per 1 million population | Percentage male | Median age (IQR) | No. of cases | Incidence rate per 1 million population | Percentage male | Median age (IQR) |
1998 | 2010 | 41.3 | 60.8 | 65 (49–75) | 1079 | 22.2 | 65.2 | 63 (46–74) | 1304 | 26.8 | 65.1 | 63 (46–73) |
1999 | 1968 | 40.3 | 61.5 | 65 (50–75) | 1066 | 21.8 | 63.7 | 63 (45–73) | 1297 | 26.6 | 65.6 | 62 (44–72) |
2000 | 2157 | 44.0 | 61.8 | 66 (50–76) | 1173 | 23.9 | 65.2 | 64 (47–75) | 1479 | 30.2 | 64.5 | 61 (42–74) |
2001 | 1995 | 40.5 | 63.6 | 64 (49–75) | 1043 | 21.2 | 68.0 | 63 (47–74) | 1256 | 25.5 | 68.4 | 62 (43–74) |
2002 | 2102 | 42.6 | 59.8 | 66 (48–76) | 1126 | 22.8 | 61.9 | 65 (47–76) | 1357 | 27.5 | 61.8 | 64 (45–75) |
2003 | 2086 | 42.0 | 62.4 | 66 (48–77) | 1035 | 20.8 | 67.1 | 66 (47–75) | 1295 | 26.1 | 67.2 | 64 (43–74) |
2004 | 2180 | 43.7 | 65.7 | 65 (47–75) | 1137 | 22.8 | 69.1 | 64 (43–75) | 1338 | 26.8 | 70.7 | 63 (42–74) |
2005 | 2228 | 44.4 | 63.2 | 65 (46–76) | 1174 | 23.4 | 66.5 | 64 (44–75) | 1384 | 27.6 | 67.5 | 63 (43–74) |
2006 | 2463 | 48.7 | 65.1 | 65 (44–77) | 1274 | 25.2 | 68.1 | 63 (42–75) | 1530 | 30.2 | 69.5 | 62 (41–75) |
2007 | 2268 | 44.5 | 65.6 | 66 (47–77) | 1224 | 24.0 | 69.3 | 64 (45–76) | 1472 | 28.9 | 69.3 | 63 (45–76) |
2008 | 2456 | 47.8 | 66.4 | 66 (48–77) | 1337 | 26.0 | 70.8 | 64 (46–76) | 1620 | 31.5 | 71.0 | 63 (45–75) |
2009 | 2531 | 48.9 | 65.9 | 65 (47–76) | 1385 | 26.7 | 68.2 | 63 (43–75) | 1690 | 32.6 | 69.5 | 62 (43–75) |
2010 | 2452 | 47.0 | 64.4 | 67 (50–78) | 1364 | 26.1 | 68.2 | 66 (49–77) | 1655 | 31.7 | 69.4 | 66 (46–76) |
2011 | 2546 | 48.4 | 66.1 | 66 (50–77) | 1470 | 27.9 | 68.4 | 66 (49–77) | 1739 | 33.1 | 67.6 | 65 (48–76) |
2012 | 2703 | 50.9 | 66.1 | 66 (50–77) | 1595 | 30.0 | 69.4 | 66 (51–77) | 2035 | 38.3 | 69.1 | 64 (46–75) |
2013 | 2773 | 51.8 | 67.0 | 67 (50–78) | 1682 | 31.4 | 69.2 | 66 (49–77) | 2074 | 38.8 | 69.9 | 65 (46–77) |
2014 | 3105 | 57.6 | 65.8 | 67 (49–78) | 1924 | 35.7 | 67.3 | 66 (47–77) | 2466 | 45.8 | 71.4 | 64 (45–76) |
2015 | 3184 | 58.6 | 65.8 | 67 (50–78) | 2054 | 37.8 | 67.7 | 66 (49–78) | 2645 | 48.7 | 68.8 | 63 (47–76) |
2016 | 3617 | 66.0 | 65.9 | 67 (48–78) | 2384 | 43.5 | 67.4 | 66 (47–77) | 3055 | 55.7 | 68.9 | 65 (47–77) |
2017 | 3746 | 67.7 | 67.2 | 67 (48–78) | 2325 | 42.0 | 69.8 | 67 (48–78) | 3061 | 55.4 | 70.8 | 66 (46–76) |