Fig. 3From: Are immune-related adverse events associated with the efficacy of immune checkpoint inhibitors in patients with cancer? A systematic review and meta-analysisMeta-analyses of the association between immune-related adverse event development and outcome. Abbreviations: HR, hazard ratio; irAEs, immune-related adverse events; non-irAEs, non-immune-related adverse events. Low grade indicates grades 1–2; severe grade indicates a grade greater than or equal to 3. aThe HR was directly presented without pooling because only one study was availableBack to article page