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Table 3 Cox proportional hazard model of the association between total sugar consumption and all-cause mortality

From: The associations of sugar-sweetened, artificially sweetened and naturally sweet juices with all-cause mortality in 198,285 UK Biobank participants: a prospective cohort study

 NumberDeaths, no.First quintile, 0.4–81.9 g, n = 39,660, HR (95% CI)Second quintile, 82–105 g, n = 39,655, HR (95% CI)Third quintile, 106–126 g, n = 39,663, HR (95% CI)Fourth quintile, 127–154 g, n = 39,650, HR (95% CI)Highest quintile, 155–1051 g, n = 39,657, HR (95% CI)p value for trend
Deaths, no.  632615599599723 
Model        
 0198,28331661 (Ref)0.96 (0.86–1.08)0.94 (0.84–1.05)0.94 (0.84–1.05)1.15 (1.03–1.27)0.034
 1197,59031501 (Ref)0.90 (0.81–1.01)0.84 (0.75–0.94)0.81 (0.73–0.91)0.95 (0.86–1.06)0.156
 2161,41523111 (Ref)1.02 (0.97–1.27)0.98 (0.87–1.15)1.00 (0.94–1.25)1.19 (0.95–1.30)0.108
 3161,41523111 (Ref)1.04 (0.91–1.19)0.99 (0.87–1.15)1.03 (0.88–1.20)1.25 (1.04–1.50)0.076
 4161,41523111 (Ref)1.05 (0.92–1.20)1.02 (0.88–1.18)1.05 (0.90–1.23)1.28 (1.06–1.55)0.057
  1. Model 0: unadjusted
  2. Model 1: adjusted for sex, age and ethnicity
  3. Model 2: model 1 also adjusted for income, highest qualification, physical activity, sedentary behaviour, total energy intake, body mass index, smoking status and alcohol intake
  4. Model 3: model 2 also adjusted for total fat intake
  5. Model 4: model 3 also adjusted for fresh fruit intake, vegetable intake, total fibre intake, red meat intake and processed meat intake
  6. Median total sugar intake: 1st quintile, 68 g; 2nd quintile, 94 g; 3rd quintile, 115 g; 4th quintile, 139 g; 5th quintile, 179 g
  7. N number, HR hazard ratio, CI confidence interval