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Fig. 3 | BMC Medicine

Fig. 3

From: Actigraphy in brain-injured patients – A valid measurement for assessing circadian rhythms?

Fig. 3

Circadian rhythmicity contrasted between datasets (a) and circadian rhythm strength contrasted between diagnoses (b).a Deviation of the patients’ peak period from 24 h. The patients’ activity rhythms were significantly better aligned with a 24-h rhythm in the uncorrected data (=less deviation from 24 h). UWS and MCS/EMCS patients did not differ in both uncorrected and corrected data (cf. Additional file 1: Figures S4 E-F). b Normalized power of the patients’ peaks closest to 24 h. UWS and MCS/EMCS patients differed in the uncorrected and corrected data. Pooling both patient groups, the normalized power did not differ between datasets (cf. Additional file 1: Figure S3). For better illustration, the data was log-transformed (right-hand y-axes); statistics were performed on the untransformed data (left-hand y-axes). Horizontal lines represent the medians, boxes the interquartile range (IQR; distance between the 1st [Q1] and 3rd quartile [Q3]), and whiskers extend at most to Q1−1.5*IQR (lower whisker) and Q3+1.5*IQR (upper whisker). Asterisks indicate significance: ***p ≤ .001, *p ≤ .05, +p ≤ .1. Abbreviations: MCS minimally conscious state, EMCS exit MCS, UWS unresponsive wakefulness syndrome

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