Skip to main content
Fig. 4 | BMC Medicine

Fig. 4

From: SerumĀ free thiols predict cardiovascular events and all-cause mortality in the general population: a prospective cohort study

Fig. 4

Associations between protein-adjusted serumĀ free thiol levels and the risk of cardiovascular (CV) events across various subgroups. Hazard ratios (HRs) are shown with corresponding 95% confidence intervals (CI). HRs represent consistently inverse associations across subgroups, with the exception of stratification by the presence of hypertension (Pinteractionā€‰<ā€‰0.001). Stratifications by BMI, albuminuria, hypertension, diabetes, and hypercholesterolemia show significant interactions. Corresponding HRs are consistently lower for subjects with a more favorable cardiovascular risk profile (i.e., lower BMI and the absence of hypertension and diabetes), whereas the presence of CVD history or albuminuria shows lower HRs as well. *HRs adjusted for potential confounding factors (sex, age, hsCRP, current smoking, systolic blood pressure, total cholesterol, diabetes, and BMI). CV-e, cardiovascular events; BMI, body mass index; eGFR, estimated glomerular filtration rate; CVD, cardiovascular disease; HR, hazard ratio; CI, confidence interval

Back to article page