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Table 4 Association of genetically predicted eGFR with serum testosterone using Mendelian randomization in the UK Biobank

From: The role of testosterone in chronic kidney disease and kidney function in men and women: a bi-directional Mendelian randomization study in the UK Biobank

Exposure

Outcome

#SNPs

Sex

Methods

Beta

95% CI

p

Genetically predicted eGFR

Serum testosterone

223

Men

MR-PRESSO

0.12*

− 0.12, 0.37

0.33

WM

0.02

− 0.27, 0.32

0.89

Women

MR-PRESSO

0.06*

− 0.18, 0.30

0.63

WM

0.09

− 0.23, 0.41

0.57