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Table 4 Association of genetically predicted eGFR with serum testosterone using Mendelian randomization in the UK Biobank

From: The role of testosterone in chronic kidney disease and kidney function in men and women: a bi-directional Mendelian randomization study in the UK Biobank

Exposure Outcome #SNPs Sex Methods Beta 95% CI p
Genetically predicted eGFR Serum testosterone 223 Men MR-PRESSO 0.12* − 0.12, 0.37 0.33
WM 0.02 − 0.27, 0.32 0.89
Women MR-PRESSO 0.06* − 0.18, 0.30 0.63
WM 0.09 − 0.23, 0.41 0.57