Table 3 Risk of incident dementia in relation to 5 units higher body mass index measured at different age categories in the Health and Retirement Study

Main model^a

0.97 (0.91–1.04)

0.91 (0.86–0.96)

0.89 (0.83–0.95)

Main model, genotyped^a

0.95 (0.86–1.06)

0.91 (0.83–1.01)

0.85 (0.73–1.00)

 PGS_BMI^b

0.96 (0.86–1.06)

0.91 (0.82–1.00)

0.83 (0.72–0.97)

 PGS_BMI and PGS_AD^c

0.96 (0.86–1.06)

0.91 (0.83–1.00)

0.83 (0.71–0.97)

 Lowest tertile

0.94 (0.78–1.13)

0.97 (0.83–1.13)

0.84 (0.64–1.10)

 Middle tertile

0.92 (0.77–1.10)

0.87 (0.73–1.03)

0.71 (0.52–0.95)

 Highest tertile

0.99 (0.84–1.16)

0.89 (0.76–1.05)

0.96 (0.77–1.19)

p value interaction

0.70

0.49

0.42