Fig. 1

Estimated birth size for children of typical mothers, across the range of maternal I:Cr concentrations. Histograms illustrate the distribution of iodine concentrations, and although the figures are curtailed at 300 μg/g, the splines (solid line) and 99% CIs (dashed lines) were drawn using data from all participants. Splines were drawn after adjustment for confounders (details in Supplemental table S1). The spline position in these figures illustrates the predicted estimate for typical participants (primiparous; White ethnic background; ‘employed and not materially deprived’; did not smoke, drink or experience complications in pregnancy; and have average BMI, age and gestation length)