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Table 1 The advancements in computer algorithms applying to cervical images

From: The challenges of colposcopy for cervical cancer screening in LMICs and solutions by artificial intelligence

Reference

Publish year

Aim of the study

Study design

Number of subjects

Image-generating devices

Type of algorithms

Outcomes

Simoes et al. [18]

2014

Classification of colposcopy images

Retrospective

170 images (training set 48; test and internal validation set 122)

Digital colposcopy

ANN

Accuracy 72.15%

Kim and Huang [19]

2013

Detection of CIN2+ from normal/CIN1

Retrospective

2000 images (normal/CIN2 1000; CIN2+ 1000)

Cervicography (discontinued)

SVM

Sensitivity 75%

Specificity 75%

Asiedu et al. [20]

2019

Detection of CIN1+ against normal

Retrospective

134 patients (training set 107; internal validation set 27)

Digital colposcopy

SVM

Accuracy 80%

Sensitivity 81.3%

Specificity 78.6%

Miyagi et al. [21]

2019

Classification of CIN1 and CIN2+

Retrospective

310 images (both using in training and internal validation set)

Traditional colposcopy

Convolutional neural networks

Accuracy 82.3%

Sensitivity 80%

Specificity 88.2%

Song et al. [22]

2015

Detection of CIN2+

Retrospective

7669 patients with < CIN2, 142 patients with CIN2+ (training set 7531; internal validation set 280)

Cervicography (discontinued)

Multimodal convolutional neural networks

Accuracy 89%

Sensitivity 83.21%

Specificity 94.79%

Schiffman et al. [23]

2019

Detection of CIN2+

Retrospective

9127 patients with < CIN2, 279 patients with CIN2+ (training set 744, internal validation set 324, rest in screening set)

Cervicography (discontinued)

Faster R-CNN

AUC 0.91