Table 1 MDR-TB cascade of care data sources and estimations, Madagascar, 2017

1. Prevalent cases

• WHO

• National drug resistance survey

• National reference laboratory data

• NTP case notification data

[1, 2, 22, 23]

61,880 (40,040–88,400)

3646 (2258–5437)

341 (61–913)

2. Reached diagnostic and treatment centre

• Country tuberculosis guidelines

• Diagnostic literature

• Locally assessed sensitivity of sputum microscopy and GeneXpert MTB/RIF

• National reference laboratory data

• NTP case notification data

[17, 19, 20, 23,24,25]

51,419 (46,744–57,250)

3563 (3197–4046)

224 (170–330)

3. Diagnosed

• National reference laboratory data

• NTP case notification data

[23, 26]

35,339 (35,124–35,570)

2485 (2443–2540)

24 (22–27)

4. Registered for treatment

• NTP clinical management data

[26]

32,427 (−)

2257 (−)

18 (−)

5. Cured or treatment completed

• NTP clinical management data

[26]

28,178 (−)

1852 (−)

8 (−)

6. Recurrence-free survival

• NTP clinical management data

• Clinical TB literature

[26, 27]

27,996 (27,774–28,108)

1670 (1448–1782)

8 (−)