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Table 3 Association of biomarkers with death at 28 days

From: sTREM-1 predicts mortality in hospitalized patients with infection in a tropical, middle-income country

Biomarkera

Unadjusted

Modified SOFA-adjustedb

OR (95% CI)

p value

OR (95% CI)

p value

IL-8

2.3 (1.9–2.9)

< 0.001

1.9 (1.5–2.4)

< 0.001

sTNFR-1

21.3 (10.6–42.8)

< 0.001

5.2 (2.3–12.1)

< 0.001

Ang-1

1.1 (0.8–1.6)

0.48

1.2 (0.8–1.8)

0.4

Ang-2

11.3 (6.6–19.3)

< 0.001

5.4 (2.8–10.3)

< 0.001

Ang-2:Ang-1

2.2 (1.7–3.0)

< 0.001

1.5 (1.1–2.2)

0.02

sTREM-1

33.0 (16.3–67.0)

< 0.001

11.2 (4.9–25.9)

< 0.001

  1. aBiomarkers were log10-transformed before regression; each biomarker was assessed in separate models
  2. bModels were adjusted for age, sex, transfer status, Charlson Comorbidity Index, and modified SOFA score