Effects of a physical activity program from diagnosis on cardiorespiratory fitness in children with cancer: a national non-randomized controlled trial

Table 4 Comparisons of cardiorespiratory fitness and physical function between children with cancer and healthy age-and sex-matched children at baseline (median of 12 days in the intervention group and 27 days in the control group)

	n	Intervention group	p value	n	Control group	p value	n	Subgroup of ambassadors	n	Historic healthy age- and sex-matched children
VO₂peak(ml/min/kg)	38	27.4 ± 6.97	< 0.0001	13	27.8 ± 8.30	< 0.0001			255	47.7 ± 7.7
Sit-to-stand repetitions)	90	25.1 ± 6.4	< 0.0001	26	18.0 ± 5.0	< 0.0001	62	31.8 ± 4.5
Timed-up-and-go (seconds)	85	4.0 ± 0.8	< 0.0001	27	5.5 ± 1.7	< 0.0001	61	3.3 ± 0.4
Right handgrip strength (kg)	103	21.4 ± 11.4	0.002	28	17.1 ± 9.7	< 0.0001	63	26.8 ± 12.8
Left handgrip strength (kg)	104	20.0 ± 10.8	< 0.0001	28	16.6 ± 10.4	< 0.0001	63	24.3 ± 11.8

VO₂peak, sit-to-stand, timed-up-and-go, and handgrip strength are reported in mean and standard deviation. The p values represent a comparison between a patient group (the intervention group and the control group) and a group of healthy children (the subgroup of ambassadors or historic healthy age- and sex-matched children)

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