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Table 1 Characteristics of preterm infants and their mothers by future childhood adiposity status at age 4 to 7 years

From: Integration of an interpretable machine learning algorithm to identify early life risk factors of childhood obesity among preterm infants: a prospective birth cohort

Characteristics

Offspring without overweight/obesity (n = 1851)

Offspring with overweight/obesity (n = 274)

p§

Boys

1076 (58.1)

186 (67.9)

< 0.01

Median (IQR) gestational weeks

36 (35–36)

36 (35–36)

0.89

Mean (SD) fetal heart rate at the last assessment

140.9 (6.3)

141.4 (5.7)

0.17

Cesarean delivery

1087 (58.7)

181 (66.1)

0.02

Mean (SD) birth weight

2.7 (0.5)

2.9 (0.5)

< 0.01

Mean (SD) birth length

48.2 (2.4)

48.6 (2.5)

0.02

Mean (SD) Apgar score at 1 min

8.5 (1.5)

8.6 (1.6)

0.37

Mean (SD) Apgar score at 5 min

9.1(1.1)

9.3 (1.0)

0.08

Duration of breast-feeding

0.06

 < 1 month

735 (39.7)

94 (34.3)

 

 1–3 months

397 (21.4)

78 (28.5)

 

 4–5 months

678 (36.6)

95 (34.7)

 

 > 6 months

41 (2.2)

7 (2.6)

 

 Formula-feeding (ever)

1773 (95.8)

254 (92.7)

0.02

Timing of solid foods introduction

0.09

 ≤ 3 months

1235 (66.7)

180 (65.7)

 

 4–6 months

554 (29.9)

91 (33.2)

 

 > 6 months

62 (3.3)

3 (1.1)

 

Trajectory of BMI Z-score change during the first year of corrected age

< 0.01

 Trajectory 1

691 (37.3)

6 (2.2)

 

 Trajectory 2

1131 (60.1)

38 (13.9)

 

 Trajectory 3

47 (2.5)

230 (83.9)

 

 Mean (SD) maternal age at pregnancy

25.3 (4.2)

24.9 (4.0)

0.12

 Mean (SD) maternal age of menarche

14.7 (1.3)

14.5 (1.3)

< 0.01

 Parity (multiparous)

357 (19.3)

40 (14.6)

0.06

Maternal education

0.46

 < High school

1357 (73.3)

191 (69.7)

 

 High school

325 (17.6)

55 (20.1)

 

 > High school

169 (9.1)

28 (10.2)

 

Maternal occupation

0.08

 Farm work/housework

1225 (66.2)

170 (62.0)

 

 Routine job

328 (17.7)

44 (16.1)

 

 Temporary work

138 (7.5)

24 (8.8)

 

 Others

160 (8.6)

36 (13.1)

 

 Median (IQR) gestational age at enrollment

10.0 (8.3–12.3)

10.1 (8.1–12.1)

0.59

 Mean (SD) maternal BMI at enrollment

20.9 (2.8)

22.0 (3.2)

< 0.01

Trajectory of BMI change during pregnancy

< 0.01

 Trajectory 1

686 (37.1)

70 (25.5)

 

 Trajectory 2

1008 (54.5)

143 (52.2)

 

 Trajectory 3

157 (8.5)

61 (22.3)

 

Trajectory of diastolic blood pressure change during pregnancy

0.87

 Trajectory 1

805 (43.5)

115 (42.0)

 

 Trajectory 2

956 (51.6)

141 (51.5)

 

 Trajectory 3

90 (4.9)

18 (6.6)

 

Trajectory of systolic blood pressure change during pregnancy

0.16

 Trajectory 1

871 (47.1)

115 (42.0)

 

 Trajectory 2

895 (48.4)

141 (51.5)

 

 Trajectory 3

85 (4.6)

18 (6.6)

 

 Mean (SD) maternal hemoglobin concentration at enrollment

120.3 (28.6)

121.2 (14.7)

0.61

Trajectory of hemoglobin concentration change during pregnancy

0.79

 Trajectory 1

304 (16.4)

47 (17.2)

 

 Trajectory 2

1449 (78.3)

215 (78.5)

 

 Trajectory 3

98 (5.3)

12 (4.4)

 
  1. Values are numbers (percentages) unless stated otherwise
  2. §Chi-square test, t test, and Wilcoxon rank-sum test were used as appropriate