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Table 3 Subgroup analyses

From: All-cause mortality in patients with long-term opioid therapy compared with non-opioid analgesics for chronic non-cancer pain: a database study

Subgroup

N (opioid)

N (non-opioid)

Death (opioid)

Death (non-opioid)

Risk difference (95% confidence interval)

Person-years follow-up (opioid)

Person-years follow-up (non-opioid)

Incidence death per 10,000 person-years (opioid)

Incidence death per 10,000 person-years (non-opioid)

Osteoarthritis

718

724

151

92

0.06 (0.03–0.09)

2250.2

2477.1

671.0

371.4

Low back pain

667

722

75

40

0.08 (0.04–0.12)

2162.0

2535.5

346.9

157.8

Pain, unspecified

651

313

141

33

0.11 (0.08–0.16)

795.5

326.8

795.5

326.8

Diabetic polyneuropathy

76

73

16

22

− 0.09 (− 0.23–0.06)

187.6

197.0

852.7

1116.7