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Fig. 3 | BMC Medicine

Fig. 3

From: Blood transcriptomic discrimination of bacterial and viral infections in the emergency department: a multi-cohort observational validation study

Fig. 3

SeptiCyte™ TRIAGE score, combined SeptiCyte™ score, blood leukocyte count and serum C-reactive protein in the ED fever cohort. Distributions of SeptiCyte™ TRIAGE score (a), combined SeptiCyte™ score (b), peripheral blood leukocyte count (c) and serum C-reactive protein (CRP) (d) for proven bacterial and viral infections. Receiver operating characteristic area under the curve (ROC AUC ± 95% confidence intervals) for discrimination of proven bacterial and viral infections using SeptiCyte™ TRIAGE score (e), combined SeptiCyte™ score (f), peripheral blood leukocyte count (g) and serum C-reactive protein (CRP) (h). Positive predictive value (PPV) and negative predictive value (NPV) of bacterial infection at different pre-test probabilities using the sensitivity and specificity derived from the maximal Youden index of the ROC curves for each of the SeptiCyte™ TRIAGE score (i), combined SeptiCyte™ score (j), peripheral blood leukocyte count (k) and serum C-reactive protein (CRP) (l)

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