Fig. 4

Estimation of bacterial and viral infection rates in different ED patient groups with a fever. a Frequency distributions of the combined (SeptiCyte™ TRIAGE and SeptiCyte™ VIRUS) score in ED fever cohort cases with proven bacterial and viral infections and in cases with no microbiological diagnosis who received empirical antibacterial treatment (group A) or recovered without antibacterial treatment (group B). b Computationally generated distributions generated by mixing different proportions of the two distinct distributions of combined SeptiCyte™ scores from cases of proven bacterial and viral infections shown in (a). c The Jensen-Shannon divergence index, used to identify the distribution in (b) that was most similar to the distributions of group A and group B shown in) (a), giving an estimate of the proportion of viral infections in each group indicated. d The relative likelihood of each individual case in group A and group B being derived from the distribution of combined SeptiCyte™ scores associated with proven bacterial or viral infections