Table 2 Summary performance metrics for SeptiCyte™ scores, WCC and CRP for discrimination of proven bacterial and viral infections in the ED cohort, at the Youden index threshold for each test

0.89 (0.81–0.97)

0.95 (0.90–1)

0.79 (0.68–0.91)

0.73 (0.61–0.86)

0.87 (0.76–0.94)

0.94 (0.86–0.98)

0.84 (0.75–0.90)

0.87 (0.79–0.93)

0.79 (0.5–0.95)

0.93 (0.66–0.99)

0.81 (0.54–0.96)

0.5 (0.25–0.75)

4.04 (1.50–19.48)

13.18 (2.53–546.5)

4.45 (1.64–22.24)

1.75 (1.05–3.77)

0.17 (0.10–0.48)

0.06 (0.02–0.22)

0.20 (0.10–0.46)

0.25 (0.09–0.84)

0.66 (0.34–0.91)

0.88 (0.51–0.99)

0.70 (0.39–0.93)

0.35 (0.15–0.62)

0.70 (0.45–0.80)

0.86 (0.64–0.96)

0.90 (0.80–0.94)

0.88 (0.69–0.95)

0.91 (0.79–0.98)

0.97 (0.87–0.99)

0.92 (0.80–0.98)

0.82 (0.73–0.91)

0.92 (0.79–095)

0.97 (0.90–0.99)

0.66 (0.46–0.79)

0.60 (0.32–0.72)