Table 1 Selected baseline characteristics of the study subjects
40–60 years (n = 777:777) | 40–50 years (n = 333:333) | 60 years (n = 444:444) | ||||
|---|---|---|---|---|---|---|
Controls | Cases | Controls | Cases | Controls | Cases | |
Clinical characteristicsa,b | ||||||
Age (years)c | 59.8 (40.3–60.3) | 59.8 (40.4–60.3) | 50.0 (40.1–50.3) | 50.0 (40.1–50.4) | 60.0 (59.7–60.3) | 60.0 (59.5–60.4) |
BMI (kg/m2)c | 25.8 (21.8–31.5) | 25.7 (21.7–31.4) | 25.5 (22.0–31.3) | 25.5 (22.0–31.3) | 26.1 (21.6–31.6) | 26.0 (21.4–31.5) |
Height (cm) | 177 (167–187) | 177 (167–186) | 179 (167–189) | 178 (168–187) | 176 (167–186) | 176 (166–186) |
Weight (kg) | 81 (66–100) | 81 (66–101) | 81 (67–101) | 81 (66–101) | 82 (65–100) | 81 (65–101) |
SBP (mmHg) | 130 (110–165) | 130 (110–165) | 125 (106–155) | 125 (105–153) | 137 (110–170) | 138 (110–170) |
DBP (mmHg) | 82 (65–100) | 83 (65–100) | 80 (64–98) | 80 (65–99) | 85 (70–100) | 85 (70–100) |
Dietary intake (FFQ)a,b | ||||||
Energy (kcal/day) | 1952 (1116–3183) | 1974 (1141–3091) | 1910 (1126–3032) | 1985 (1155–3140) | 1972 (1116–3262) | 1940 (1129–3082) |
Total fat (g/day) | 74.1 (39.4–133) | 75.2 (40.3–129) | 75.4 (42.7–133) | 77.7 (37.6–129) | 73.2 (36.4–135) | 72.6 (40.5–131) |
FA C14:0 (g/day) | 3.34 (1.34–7.28) | 3.30 (1.51–7.18) | 3.64 (1.59–7.30) | 3.60 (1.61–7.48) | 3.08 (1.25–7.22) | 3.14 (1.44–6.58) |
FA C16:0 (g/day) | 14.9 (7.39–27.9) | 15.1 (7.89–28.1) | 16.3 (8.54–28.3) | 16.8 (8.11–28.5) | 14.1 (7.02–27.2) | 13.8 (7.73–27.4) |
FA C17:0 (g/day) | 0.13 (0.03–0.33) | 0.13 (0.04–0.34) | 0.15 (0.04–0.33) | 0.14 (0.04–0.35) | 0.12 (0.03–0.34) | 0.13 (0.04–0.32) |
FA C18:2 (g/day) | 7.23 (3.62–15.0) | 7.24 (3.64–14.8) | 7.74 (4.28–17.2) | 7.99 (3.82–15.7) | 6.90 (3.39–13.4) | 6.61 (3.51–14.1) |
FA C20:4 (g/day) | 0.07 (0.03–0.17) | 0.07 (0.03–0.17) | 0.08 (0.03–0.18) | 0.08 (0.04–0.18) | 0.07 (0.03–0.15) | 0.07 (0.03–0.16) |
Blood parameters (OGTT; mmol/L)a,b | ||||||
Glucose (0 h) | 5.5 (4.6–6.6) | 5.5 (4.5–6.7) | 5.4 (4.6–6.4) | 5.4 (4.4–6.6) | 5.5 (4.7–6.7) | 5.5 (4.5–6.8) |
Glucose (2 h) | 6.5 (4.0–9.5) | 6.4 (4.1–9.3) | 6.3 (3.9–8.6) | 6.0 (3.8–8.7) | 6.7 (4.1–10.3) | 6.7 (4.4–9.8) |
Status of glucose metabolisma,b | ||||||
NGT | 541 (70) | 580 (75) | 255 (77) | 272 (82) | 286 (65) | 308 (69) |
IFG | 67 (9) | 70 (9) | 26 (8) | 27 (8) | 41 (9) | 43 (10) |
IGT | 138 (18) | 93 (12) | 46 (14) | 23 (7) | 92 (21) | 70 (16) |
T2D | 27 (3) | 31 (4) | 5 (1) | 10 (3) | 22 (5) | 21 (5) |