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Table 2 Case characteristics at the time of diagnosis

From: Identification of metabolites associated with prostate cancer risk: a nested case-control study with long follow-up in the Northern Sweden Health and Disease Study

 

N(%)

40–60 years (n = 777)

40–50 years (n = 333)

60 years (n = 444)

Follow-up time

 ≥ 5, < 10 years

368 (47)

118 (35)

250 (56)

 ≥ 10 years

409 (53)

215 (65)

194 (44)

Age at diagnosis

 < 65 years

282 (36)

276 (83)

6 (1)

 ≥ 65 years

495 (64)

57 (17)

438 (99)

Tumour differentiationa

 Poorly

114 (15)

33 (10)

81 (18)

 Highly/intermediately

656 (84)

299 (90)

357 (81)

 Missing

7 (1)

1 (0)

6 (1)

Primary tumour

 Non-assessed (TX)

15 (2)

9 (3)

6 (1)

 Non-palpable (T1)

433 (56)

209 (63)

224 (50)

 Localised (T2)

248 (32)

94 (28)

154 (35)

 Non-localised (T3–T4)

74 (9)

18 (5)

56 (13)

 Missing

7 (1)

3 (1)

4 (1)

Serum PSA

 ≤ 50 ng/mL

703 (90)

314 (94)

389 (88)

 > 50 ng/mL

67 (9)

18 (6)

49 (11)

 Missing

7 (1)

1 (0)

6 (1)

Disease aggressivenessb

 Non-aggressive

608 (78)

289 (87)

319 (72)

 Aggressive

169 (22)

44 (13)

125 (28)

  1. aPoorly differentiated tumour: Gleason’s sum score 8–10 or grade 3 (in the three-level WHO grading system). Highly/intermediately differentiated tumour: Gleason’s sum score ≤ 7 or grade 1–2 (in the three-level WHO grading system)
  2. bAggressive case subjects: poorly differentiated (Gleason sum’s score 8–10 or grade 3), non-localised tumour (i.e. primary tumour stage T3–4), lymph node metastasis (N1), bone metastasis (M1), serum PSA concentration > 50 ng/mL or fatal prostate cancer by March 2007