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Table 3 Input parameters used to model health outcomes

From: Cost-effectiveness of inhaled oxytocin for prevention of postpartum haemorrhage: a modelling study applied to two high burden settings

 

Bangladesh

Ethiopia

Value

Source

Value

Source

Number of women of reproductive age (15–49) (‘000)

44,998a

UN data 2017 [34]

24,150a

UN data 2017 [34]

Fertility rate of women of reproductive age (15–49)

73a

DHS 2015 [35]

141a

DHS 2016 [36]

Maternal mortality ratiob

205a

BMMS 2016 [13]

412

EmONC assessment 2016 [17]

Maternal deaths due to PPH

27%a

BMMS 2016 [13]

31%

EmONC assessment 2016 [17]

Child survival rate (to age of 12 months)

 If mother survives

92.4%

Ronsmans et al. 2010 [37]

95.6%

Moucheraud et al. 2015 [38]

 If mother dies within 42 days of childbirth

29.6%

Ronsmans et al. 2010 [37]

18.75%

Moucheraud et al. 2015 [38]

Incidence of PPH without preventative uterotonics

 Mild

11.3%

Gallos et al. 2018 [8]

11.3%

Gallos et al. 2018 [8]

 Severe

5.9%

Gallos et al. 2018 [8]

5.9%

Gallos et al. 2018 [8]

Risk ratio of mild PPH with uterotonics for prevention

 Injectable oxytocin

0.61

Gallos et al. 2018 [8]

0.61

Gallos et al. 2018 [8]

 Misoprostol

0.75

Gallos et al. 2018 [8]

0.75

Gallos et al. 2018 [8]

 Inhaled oxytocin

0.61

Assumption

0.61

Assumption

Risk ratio of severe PPH with uterotonics for prevention

 Injectable oxytocin

0.61

Gallos et al. 2018 [8]

0.61

Gallos et al. 2018 [8]

 Misoprostol

0.73

Gallos et al. 2018 [8]

0.73

Gallos et al. 2018 [8]

 Inhaled oxytocin

0.61

Assumption

0.61

Assumption

  1. UN United Nations, DHS Demographic and Health Survey, BMMS Bangladesh Maternal Mortality Survey, EmONC Emergency Obstetric and Neonatal Care, PPH postpartum haemorrhage
  2. aAge-specific values used (5-year brackets)
  3. bDeaths per 100,000 live births