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Table 3 Input parameters used to model health outcomes

From: Cost-effectiveness of inhaled oxytocin for prevention of postpartum haemorrhage: a modelling study applied to two high burden settings

  Bangladesh Ethiopia
Value Source Value Source
Number of women of reproductive age (15–49) (‘000) 44,998a UN data 2017 [34] 24,150a UN data 2017 [34]
Fertility rate of women of reproductive age (15–49) 73a DHS 2015 [35] 141a DHS 2016 [36]
Maternal mortality ratiob 205a BMMS 2016 [13] 412 EmONC assessment 2016 [17]
Maternal deaths due to PPH 27%a BMMS 2016 [13] 31% EmONC assessment 2016 [17]
Child survival rate (to age of 12 months)
 If mother survives 92.4% Ronsmans et al. 2010 [37] 95.6% Moucheraud et al. 2015 [38]
 If mother dies within 42 days of childbirth 29.6% Ronsmans et al. 2010 [37] 18.75% Moucheraud et al. 2015 [38]
Incidence of PPH without preventative uterotonics
 Mild 11.3% Gallos et al. 2018 [8] 11.3% Gallos et al. 2018 [8]
 Severe 5.9% Gallos et al. 2018 [8] 5.9% Gallos et al. 2018 [8]
Risk ratio of mild PPH with uterotonics for prevention
 Injectable oxytocin 0.61 Gallos et al. 2018 [8] 0.61 Gallos et al. 2018 [8]
 Misoprostol 0.75 Gallos et al. 2018 [8] 0.75 Gallos et al. 2018 [8]
 Inhaled oxytocin 0.61 Assumption 0.61 Assumption
Risk ratio of severe PPH with uterotonics for prevention
 Injectable oxytocin 0.61 Gallos et al. 2018 [8] 0.61 Gallos et al. 2018 [8]
 Misoprostol 0.73 Gallos et al. 2018 [8] 0.73 Gallos et al. 2018 [8]
 Inhaled oxytocin 0.61 Assumption 0.61 Assumption
  1. UN United Nations, DHS Demographic and Health Survey, BMMS Bangladesh Maternal Mortality Survey, EmONC Emergency Obstetric and Neonatal Care, PPH postpartum haemorrhage
  2. aAge-specific values used (5-year brackets)
  3. bDeaths per 100,000 live births