Table 1 Description of the HELIX study participants (n = 1203)
From: In utero and childhood exposure to tobacco smoke and multi-layer molecular signatures in children
Variable | n (%) or mean (SD) |
|---|---|
Cohort | |
BiB (UK) | 176 (14.6) |
EDEN (France) | 171 (14.2) |
INMA (Spain) | 215 (17.9) |
KANC (Lithuania) | 189 (15.7) |
MoBa (Norway) | 255 (21.2) |
RHEA (Greece) | 197 (16.4) |
Child sex | |
Female | 547 (45.5) |
Male | 656 (54.5) |
Child age (years) | 8.1 (1.6) |
Child zBMI* | 0.4 (1.2) |
Child ancestry | |
European | 1083 (90.1) |
Pakistani or Asian | 93 (7.7) |
Others | 27 (2.2) |
Maternal age (years) | 30.8 (4.8) |
Maternal BMI categories | |
< 18.5 | 46 (3.8) |
18.5–24.9 | 691 (57.4) |
25–29.9 | 295 (24.5) |
≥ 30 | 171 (14.2) |
Maternal education | |
Low | 162 (13.5) |
Medium | 421 (35.0) |
High | 620 (51.5) |
Pregnancy: any maternal smoking in pregnancy | |
No | 1027 (85.4) |
Yes | 176 (14.6) |
Pregnancy: sustained maternal smoking in pregnancy | |
No | 1027 (90.0) |
Yes | 114 (10.0)** |
Childhood: global-SHS | |
No | 777 (64.6) |
Yes | 426 (35.4) |
Childhood: urinary cotinine | |
Not detected (no) | 993 (82.5) |
Detected (yes) | 210 (17.5) |
Number of omics datasets | |
6 | 834 (69.3) |
4 or 5 | 282 (23.4) |
2 or 3 | 25 (2.2) |
1 | 62 (5.10) |