From: Seasonal influenza vaccination in Kenya: an economic evaluation using dynamic transmission modelling

Item | Measure | Value | Distribution | Reference |
---|---|---|---|---|

Disease states
| ||||

Proportion of influenza cases that develop any clinical symptoms | Mean (95% CI) | 0.669 (0.583–0.745) | Normal | [27] |

Proportion of influenza cases that develop upper respiratory tract symptoms/mild illness | Mean (95% CI) | 0.588 (0.455–0.708) | Normal | [27] |

Proportion of influenza cases that develop lower respiratory tract symptoms/severe illness | Mean (95% CI) | 0.210 (0.140–0.303) | Normal | [27] |

Proportion of influenza cases with severe illness that die while hospitalised | ||||

< 1 year
| Mean (95% CI) | 0.0274 (0–0.0616) | Truncated normal | Influenza SARI surveillance dataset (2010–2018) |

1–5 years
| Mean (95% CI) | 0.0091 (0–0.0322) | ||

6–14 years
| Mean (95% CI) | 0.0108 (0–0.0902) | ||

15–20 years
| Mean (95% CI) | 0 (0–0.1116) | ||

20–49 years
| Mean (95% CI) | 0.0331 (0–0.0818) | ||

≥ 50 years
| Mean (95% CI) | 0.1818 (0.0909–0.3080) | ||

All ages
| Mean (95% CI) | 0.0200 (0.0035–0.0373) | ||

Proportion of deaths due to a respiratory illness that occur in a health facility | ||||

< 1 year
| Mean (95% CI) | 0.2794 (0.2451–0.3140) | Normal | Siaya health demographic and surveillance site dataset (2010–2016) |

1–5 years
| Mean (95% CI) | 0.2899 (0.2471–0.3349) | ||

6–14 years
| Mean (95% CI) | 0.4361 (0.3534–0.5278) | ||

15–20 years
| Mean (95% CI) | 0.5250 (0.3750–0.6795) | ||

20–49 years
| Mean (95% CI) | 0.5067 (0.4626–0.5525) | ||

≥ 50 years
| Mean (95% CI) | 0.2715 (0.2421–0.3012) | ||

All ages
| Mean (95% CI) | 0.3287 (0.3106–0.3474) | ||

Health care utilisation events
| ||||

Proportion of symptomatic influenza cases who attend outpatient clinic | ||||

0–5 years
| Mean (95% CI) | 0.475 (0.39–0.60) | Normal | [29] |

6–12 years
| Mean (95% CI) | 0.118 (0.09–0.17) | ||

13–17 years
| Mean (95% CI) | 0.088 (0.06–0.13) | ||

18–24 years
| Mean (95% CI) | 0.035 (0.02–0.08) | ||

25–44 years
| Mean (95% CI) | 0.034 (0.02–0.07) | ||

45–64 years
| Mean (95% CI) | 0.027 (0.01–0.05) | ||

≥ 65 years
| Mean (95% CI) | 0.036 (0.02–0.07) | ||

Proportion of symptomatic influenza cases who are hospitalised | ||||

0–5 years
| Mean (95% CI) | 0.0102 (0.0089–0.0117) | Normal | [29] |

6–12 years
| Mean (95% CI) | 0.0007 (0.0006–0.0010) | ||

13–17 years
| Mean (95% CI) | 0.0006 (0.0004–0.0011) | ||

18–24 years
| Mean (95% CI) | 0.0008 (0.0006–0.0010) | ||

25–44 years
| Mean (95% CI) | 0.0021 (0.0018–0.0024) | ||

45–64 years
| Mean (95% CI) | 0.0026 (0.0020–0.0033) | ||

≥ 65 years
| Mean (95% CI) | 0.0033 (0.0025–0.0044) | ||

Proportion of outpatient influenza cases who purchased medication prior to clinic visit | Proportion | 0.718 | Fixed value | [30] |

Proportion of hospitalised influenza cases who sought care after discharge from hospital | Proportion | 0.105 | Fixed value | [30] |

Proportion of non-medically attended influenza cases where household members missed work due to illness* | Proportion | Not known | – | – |

Proportion of outpatient influenza cases where household members missed work due to illness | Proportion | 0.518 | Fixed value | [30] |

Proportion of hospitalised influenza cases where household members missed work due to illness | Proportion | 0.848 | Fixed value | [30] |

Proportion of non-medically attended influenza cases where household members paid for childcare during illness* | Proportion | Not known | – | – |

Proportion of outpatient influenza cases where household members paid for childcare during illness | Proportion | 0.18 | Fixed value | [30] |

Proportion of hospitalised influenza cases where household members paid for childcare during illness | Proportion | 0.29 | Fixed value | [30] |