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Table 2 Proportion of patients who received guideline-indicated treatment for which they were eligible according to comorbidity

From: Association of treatments for acute myocardial infarction and survival for seven common comorbidity states: a nationwide cohort study

Guideline-indicated care

Treatments received % (N)

Diabetes mellitus

COPD or asthma

Hypertension

Chronic heart failure

Chronic renal failure

Cerebrovascular disease

Peripheral vascular disease

Number of comorbidities

Pharmacological therapies

0

1

2 ≤

 Acute aspirin

89.8 (66,818)

90.7 (54,297)

91.3 (182,918)

87.2 (14,865)

87.9 (14,936)

88.5 (24,549)

88.2 (13,341)

86.4 (201,860)

91.0 (155,972)

90.1 (91,927)

 Aspirin at discharge

86.2 (88,601)

86.1 (64,560)

86.8 (225,028)

81.5 (21,971)

84.2 (20,580)

84.0 (35,427)

84.5 (19,439)

85.0 (207,794)

86.4 (178,134)

85.8 (124,459)

 P2Y12 inhibitors at discharge

40.5 (41,639)

38.6 (29,058)

39.8 (102,566)

31.9 (8669)

42.7 (10,609)

36.6 (15,726)

35.6 (8199)

38.1 (81,619)

38.3 (77,834)

39.4 (57,546)

 β-blockers at discharge

72.0 (32,712)

56.7 (13,980)

74.9 (90,334)

71.4 (16,417)

67.6 (6994)

66.3 (12,766)

67.2 (7173)

75.2 (107,956)

74.2 (73,120)

69.2 (44,117)

 ACE inhibitors/ARBs at discharge

82.6 (81,177)

78.2 (37,411)

80.6 (136,249)

77.5 (19,599)

72.0 (10,092)

74.9 (20,538)

76.9 (12,333)

74.7 (119,461)

77.8 (97,090)

80.7 (90,851)

 Statins at discharge

84.8 (89,259)

83.5 (64,424)

85.0 (224,238)

77.0 (21,627)

80.7 (20,249)

81.5 (35,656)

83.0 (19,728)

82.6 (203,064)

84.1 (175,625)

83.8 (124,997)

Aldosterone antagonists

 At discharge

30.1 (520)

33.4 (117)

32.6 (519)

38.1 (408)

N/A

33.0 (114)

30.0 (68)

0.0 (0)

30.5 (151)

32.6

6 (623)

 At admission or discharge

34.5 (597)

37.7 (132)

36.9 (587)

42.3 (453)

N/A

36.4 (126)

35.2 (80)

0.0 (0)

33.3 (165)

36.8

8 (708)

Non-invasive therapies

 Echocardiogram

56.7 (65,980)

56.6 (48,031)

57.5 (165,339)

54.2 (17,154)

56.7 (16,429)

53.5 (26,006)

57.7 (15,145)

52.0 (140,591)

55.7 (126,655)

57.1 (94,299)

 ECG

95.5 (116,764)

95.7 (85,337)

96.0 (290,259)

93.8 (31,722)

96.1 (29,804)

95.6 (49,612)

95.1 (26,268)

93.9 (263,563)

95.6 (227,863)

95.7 (167,033)

 Cardiac rehabilitation

73.2 (82,843)

73.8 (60,629)

75.6 (212,835)

62.8 (18,560)

66.0 (17,914)

67.5 (31,024)

72.2 (18,296)

74.8 (200,239)

76.0 (169,622)

72.0 (114,624)

 Smoking cessation advice

16.7 (9464)

19.4 (9819)

17.4 (24,966)

8.3 (1248)

11.8 (1461)

14.0 (3326)

16.6 (2693)

20.2 (32,897)

18.4 (22,015)

15.9 (13,102)

 Dietary advice

34.8 (40,140)

32.7 (27,584)

33.7 (96,587)

26.2 (8066)

35.0 (9796)

30.7 (14,630)

30.9(8052)

28.2 (76,044)

32.1 (72,932)

33.6 (54,844)

Invasive therapies

 Early invasive coronary procedures

51.2 (59,241)

48.6 (41,003)

54.4 (157,090)

28.7 (8864)

36.2 (10,158)

37.9 (18,190)

46.4 (12,145)

57.7 (157,354)

55.5 (126,868)

46.9 (76,944)

Cumulative treatment score—median (IQR)

66.7 (50.0–87.5)

66.7 (50.0–85.7)

66.7 (54.5–87.5)

60.0 (42.9–80.0)

63.6 (45.5–83.3)

62.5 (45.5–81.8)

63.6 (50.0–83.3)

66.7 (50.0–81.8)

66.7 (50.0–85.7)

66.7 (50.0–85.7)

Percentage of optimal care receipt

14.3 (14,449)

14.0 (12,512)

15.1 (45,657)

8.6 (2916)

13.2 (4101)

12.3 (6377)

13.2 (3655)

13.0 (36,413)

14.5 (34,599)

14.0 (24,355)

  1. COPD chronic obstructive pulmonary disease, ACE inhibitors angiotensin-converting enzyme inhibitors, ARB angiotensin receptor blocker, ECG electrocardiogram, N/A not applicable as do not meet eligibility criteria; full eligibility criteria in appendices; smoking cessation advice given to those with smoking history; acute aspirin includes only those with direct admission who were not already on aspirin or contraindicated; early invasive coronary procedures include primary PCI or thrombolysis within 12 h for STEMI and coronary angiography or PCI within 72 h for NSTEMI patients; patients were classified as ineligible if a treatment was listed as contraindicated, not indicated, or not applicable; if the patient declined treatment as recorded in MINAP; or if the patient was hospitalised prior to the publication year of treatment recommendation in the guidelines