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Table 3 The association between hyperthyroidism and mammographic density among KARMA women without a cancer diagnosis (n = 51,928)

From: Hyperthyroidism is associated with breast cancer risk and mammographic and genetic risk predictors

 

No

Yes

OR (95% CI)

Model 1

Model 2

Model 3

Mammographic density

Q1

12,797

186

1.00 (REF)

1.00 (REF)

1.00 (REF)

Q2

12,801

182

0.98 (0.80–1.20)

1.10 (0.89–1.36)

1.09 (0.88–1.35)

Q3

12,807

174

0.94 (0.76–1.15)

1.17 (0.93–1.48)

1.16 (0.92–1.47)

Q4

12,825

156

0.84 (0.68–1.04)

1.15 (0.88–1.51)

1.14 (0.87–1.49)

Pfor square root continuous

  

0.13

0.13

0.20

  1. Model 1 is the univariate model. Model 2 adjusted for age and BMI. Model 3 further adjusted for age at menarche, number of births, family history of breast cancer, hormone replacement therapy use, oral contraceptive use, and benign breast disease