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Table 2 Incremental cost-effectiveness of the lifestyle intervention versus control group over 2 years

From: Cost-effectiveness of a lifestyle intervention in high-risk individuals for diabetes in a low- and middle-income setting: Trial-based analysis of the Kerala Diabetes Prevention Program

  Cost per diabetes case prevented Cost per QALY gained
Health system perspective Societal perspective Health system perspective Societal perspective
Base-case analysis
 Without discounting 95.2 295.1 50.0 155.0
 With discounting (3% per annum) 95.1 292.5 49.0 150.8
Sensitivity analyses
Cost of group sessions only
  10% increase 157.1 357.0 82.5 187.5
  20% increase 219.0 414.1 115.0 217.5
  30% increase 276.1 476.0 145.0 250.0
  10% decrease 38.1 238.0 20.0 125.0
  20% decrease Dominated* 176.1 Dominated* 92.5
  30% decrease Dominated* 114.2 Dominated* 60.0
Intervention effectiveness only
  10% increase 87.0 269.7 45.5 140.9
  20% increase 80.0 248.0 41.7 129.2
  30% increase 74.0 229.4 38.5 119.2
  10% decrease 105.2 326.1 55.6 172.2
  20% decrease 117.6 364.6 62.5 193.8
  30% decrease 133.4 413.5 71.4 221.4
Both cost of group sessions and intervention effectiveness
  10% increase 143.6 326.3 75.0 170.5
  20% increase 184.0 348.0 95.8 181.3
  30% increase 214.6 370.0 111.5 192.3
  10% decrease 42.1 263.0 22.2 138.9
  20% decrease Dominated* 217.6 Dominated* 115.6
  30% decrease Dominated* 160.1 Dominated* 85.7
Discounting
  5% per annum 116.8 292.5 60.5 151.5
  10% per annum 169.4 292.7 88.4 152.7
MI analysis
  Lifestyle intervention vs. control group 99.2 302.1 56.0 157.5
  1. QALY quality-adjusted life year, MI multiple imputation
  2. *Lifestyle intervention was less costly and more effective than the control group