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Table 2 Calcification at different locations and the risk of mortality among women and men

From: Arterial calcification at multiple sites: sex-specific cardiovascular risk profiles and mortality risk—the Rotterdam Study

 

All-cause mortality

Cardiovascular mortality

Non-cardiovascular mortality

Women

(Ncases/Natrisk = 193/1239)

(Ncases/Natrisk = 64/1239)

(Ncases/Natrisk = 129/1239)

 CAC

1.33 (0.96–1.82)

1.35 (0.78–2.35)

1.31 (0.89–1.94)

 AAC

1.43 (1.04–1.97)

1.39 (0.80–2.43)

1.45 (0.98–2.15)

 ECAC

1.46 (1.07–2.00)

2.11 (1.22–3.66)

1.22 (0.82–1.80)

 ICAC

1.33 (0.95–1.86)

1.95 (1.08–3.51)

1.11 (0.73–1.67)

 VBAC

1.23 (0.89–1.70)

1.28 (0.74–2.22)

1.21 (0.81–1.80)

 AVC

1.15 (0.85–1.57)

2.05 (1.21–3.49)

0.85 (0.57–1.26)

Men

(Ncases/Natrisk = 259/1118)

(Ncases/Natrisk = 70/1118)

(Ncases/Natrisk = 189/1118)

 CAC

1.36 (1.04–1.79)

2.24 (1.33–3.78)

1.13 (0.82–1.58)

 AAC

1.60 (1.21–2.10)

2.02 (1.19–3.43)

1.48 (1.07–2.04)

 ECAC

1.43 (1.10–1.86)

1.74 (1.06–2.85)

1.34 (0.98–1.84)

 ICAC

1.34 (1.03–1.75)

2.11 (1.27–3.52)

1.13 (0.83–1.56)

 VBAC

1.43 (1.10–1.88)

1.34 (0.80–2.23)

1.48 (1.08–2.03)

 AVC

1.20 (0.92–1.56)

1.52 (0.94–2.48)

1.10 (0.78–1.50)

  1. Adjusted for age, cohort, scanner, body mass index, systolic blood pressure, diastolic blood pressure, smoking status, glucose, total cholesterol, HDL cholesterol, antidiabetic therapy, blood pressure, and/or lipid-lowering medication use, and history of cardiovascular disease. Values represent hazard ratios (95% confidence intervals) for a higher burden of each component and for the upper quartile versus the lowest three quartiles (CAC, AAC, ECAC, ICAC, AVC) or the presence of calcification (VBAC)
  2. CAC coronary artery calcification, AAC aortic arch calcification, ECAC extracranial carotid artery calcification, ICAC intracranial carotid artery calcification, VBAC vertebrobasilar artery calcification, AVC aortic valve calcification