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Table 3 Regional sero-prevalence (ages 2–10 years) by antigen and all-age incidence rates for clinical malaria and Pf infection. Mean sero-prevalence (%) and incidence rates with 95% CI shown in parentheses

From: Antibody responses to a suite of novel serological markers for malaria surveillance demonstrate strong correlation with clinical and parasitological infection across seasons and transmission settings in The Gambia

 

West Coast Region (WCR)

Upper River Region (URR)

July 2013

December 2013

July 2013

December 2013

Clinical incidence rate

0.08 (0.04–0.21)

0.14 (0.04–0.44)

0.13 (0.04–0.39)

0.21 (0.1–0.51)

Pf infection rate

0.23 (0.13–0.39)

0.67 (0.40–1.13)

0.56 (0.42–0.74)

2.87 (2.36–3.50)

Sero-prevalence (ages 2–10 years)

 

n = 205

n = 197

n = 275

n = 324

Etramp5.Ag1

4.4% (1.6–7.2)

13.7% (8.9–18.5)

8.7% (5.4–12.1)

33.3% (27.4–39.3)

GEXP18

11.7% (7.3–16.1)

12.7% (8.0–17.3)

25.1% (20.0–30.2)

36.3% (30.2–42.3)

HSP40.Ag1

5.4% (2.3–8.5)

6.1% (2.8–9.4)

8.4% (5.1–11.6)

23.8% (18.4–29.1)

Rh2.2030

1.0% (0.0–2.3)

1.0% (0.0–2.4)

9.8% (6.3–13.3)

25.4% (19.9–30.9)

EBA175

1.5% (0.0–3.1)

1.0% (0.0–2.4)

7.3% (4.2–10.3)

15.8% (11.2–20.5)

PfMSP119

2.9% (0.6–5.2)

8.1% (4.3–11.9)

5.1% (2.5–7.7)

22.1% (16.8–27.3)

PfAMA1

4.4% (1.6–7.2)

4.1% (1.3–6.8)

17.8% (13.3–22.3)

33.3% (27.4–39.3)

PfGLURP.R2

4.4% (1.6–7.2)

8.1% (4.3–11.9)

16.4% (12.0–20.7)

30.4% (24.6–36.2)