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Table 5 Odds of clinical malaria and asymptomatic infection by individual-level serological status, unadjusted and adjusted for age group (< 5 years, 5–15 years, and > 15 years) and LLIN use in the last 24 h

From: Antibody responses to a suite of novel serological markers for malaria surveillance demonstrate strong correlation with clinical and parasitological infection across seasons and transmission settings in The Gambia

Odds of clinical malaria or asymptomatic infection amongst sero-positive individuals, by antigen
  Unadjusted Adjusted
OR 95% CI p value aOR 95% CI p value
Etramp5.Ag1
Clinical malaria 5.88 3.44–10.03 < 0.001 4.60 2.98–7.12 < 0.001
Asymptomatic infection 3.20 2.64–3.88 < 0.001 3.33 2.72–4.08 < 0.001
GEXP18
Clinical malaria 2.57 1.44–4.61 0.002 1.48 0.90–2.41 0.122
Asymptomatic infection 2.94 2.38–3.64 < 0.001 3.12 2.50–3.90 < 0.001
HSP40.Ag1
Clinical malaria 1.67 0.88–3.18 0.119 0.99 0.59–1.65 0.956
Asymptomatic infection 2.53 2.06–3.10 < 0.001 2.64 2.09–3.33 < 0.001
Rh2.2030
Clinical malaria 2.20 1.10–4.38 0.025 1.28 0.77–2.12 0.338
Asymptomatic infection 2.45 1.98–3.03 < 0.001 3.06 2.40–3.89 < 0.001
EBA175
Clinical malaria 1.37 0.67–2.81 0.390 1.54 0.86–2.75 0.147
Asymptomatic infection 2.09 1.74–2.51 < 0.001 2.86 2.21–3.72 < 0.001
PfMSP119
Clinical malaria 3.83 1.95–7.51 < 0.001 4.09 2.60–6.44 < 0.001
Asymptomatic infection 2.29 1.82–2.88 < 0.001 2.49 1.90–3.27 < 0.001
PfAMA1
Clinical malaria 2.21 1.25–3.90 0.006 2.32 1.40–3.85 0.001
Asymptomatic infection 2.62 2.12–3.24 < 0.001 3.80 2.95–4.90 < 0.001
PfGLURP.R2
Clinical malaria 2.17 1.28–3.68 0.004 3.12 2.12–4.59 < 0.001
Asymptomatic infection 2.38 1.96–2.89 < 0.001 3.80 2.92–4.95 < 0.001